Kyle Edmund defeated the Roger Cup in the opening round, suffered the loss of 6-1 6-2 by Dougo Schwartzman.
After the rain delay, the badge of Argentina No. 11 on Monday rejected the British No.1 in an hour.
Admired shot-out, Afridi got out, he lost his first service game as World No. 12 participated in the 3-0 lead.
England got the 16th position by ATP, making it the fourth game score board, but it broke in sixth and lost the set.
Edward, who was pushed by Andy Murray at the Academy of Second and Second ODI a week before a goodbye, appears to be some mixture due to the resume in the game.
However, with the second set level of 2-2, the Schwartzman broke Britain’s service, then re-release the next three games to close the match.